Bethesda House provides space on-site for a variety of partner agencies that have satellite programs at Bethesda House. Partners include: Alliance for Positive Health, Schenectady County Health Dept., Cornell Cooperative Extension, the YWCA, CDPHP Insurance, Fidelis Insurance, and the Legal Aid Society of NENY.

Bethesda House participates in the Regional Homeless Management Information System, the Homeless Services Planning Board, the Schenectady County Ten-Year Plan to End Homelessness, the Evictions Task Force, the County Food Providers, Adults at Risk Committee, and Schenectady Coalition for a Healthy Community.

The following is a list of partnerships: